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Orlistat generico de esperazione all'età esperante e con ils s'agissent ci sono di mani. It seems obvious that the present invention can serve as a preventive and therapy for certain kinds of diabetes based on a particular metabolic disorder which appears to be associated with a particular type of human anatomy. According to an illustrated embodiment of the invention, an agent is administered to a man with obesity particular metabolic disorder, the agent to promote weight loss of said man or to prevent type 2 diabetes. The agent is preferably formulated to be delivered by intravenous infusion. An example of such agent is niacin. Although the may be administered intravenously, it can also be administered subcutaneously (s.c.) or orally. The same agent is preferably administered simultaneously with, or prior to, a weight loss campaign of such a nature that would result in a sustained reduction weight said man during such campaigns relative to the condition of prior administration agent. According to another embodiment of the present invention, said agent is administered to a man with obesity type 2 diabetes. An example of such agent is a β-cell blocking agent. An example of such a β-ce